top of page


38. A. De, T. Manna, S. C. Debnath, S. M. Husain* Organophotoredox-catalyzed stereoselective reductive dimerization of chromone-2-carboxylic esters New Journal of Chemistry 2024, 48, 1902-1906. DOI:

chromone TOC.tif

36. A. Rajput, T. Manna, A. Mondal, A. De, J. Mondal, S. M. Husain* Biocatalytic Access to Chiral Benzazepines Using Imine Reductases ACS Catalysis 2023, 13, 9, 6185–6194. DOI:


33. A. De,+ N. Saha,+ T. Manna, V. Singh, S. M. Husain* Highly Efficient One-Pot Multienzyme Cascades for the Stereoselective Synthesis of Natural Naphthalenones  ACS Catalysis 2022, 12, 19, 12179-12185. DOI: +equal contributions


28. S. K. Singh, A. Rajput, Arijit De, T. Chakraborti S. M. Husain* Promiscuity of an Unrelated Anthrol Reductase of Talaromyces islandicus WF-38-12 Cat. Sci. & Technology 202111, 474-478. DOI:

Graphic TOC.tif

26. S. K. Singh, A. Mohammad, O. A. Alghamdi, S. M. Husain* New Approaches for targeting drug resistance through drug combination Book Chapter in Combination Therapy Against Multidrug Resistance 2020 Edited by M. Y. Wani & A. Ahmed Published by Elsevier (978-0-12-820576-1)

Book chapter.jpg

25. A. Mondal,+ S. K. Singh,+ N. Saha, S. M. HusainSynthesis of Racemic Dihydroanthracen-1(2H)-ones using Sodium Borohydride in Water  Eur J. Org. Chem. 2020, 2425-2430. DOI: 10.1002/ejoc.202000096 Very Important Paper

TOC-rugulosin Final.tif

23. S. K. Singh,+ A. Mondal,+ N. Saha, S. M. HusainIdentification and Characterization of an Anthrol Reductase from Talaromyces islandicus (Penicillium islandicum) WF-38-12  Green Chemistry 2019, 21, 6954-6959. DOI: 10.1039/C9GC03072G

TOC-revised-Green Chemistry-2019.jpg

22. S. M. Husain,+ A. Präg,+A. Linnenbrink, A. Bechthold, M. Müller  Insights into the Role of Ketoreductases in the Biosynthesis of Partially Reduced Bacterial Aromatic Polyketides ChemBioChem 2020, 21, 780-784.  DOI:

TOC GTRI-02.jpg

21. A. Mondal,+ N. Saha,+ A. Rajput, S. K. Singh, B. Roy,  S. M. HusainChemoenzymatic Reduction of Citreorosein and its Implications for Aloe-Emodin and Rugulosin C (Bio)synthesis Org. Biomol. Chem. 2019, 17, 8711-8715. DOI: 10.1039/C9OB01690B 

TOC-new-for website.jpg

19. S. K. Singh, S. M. HusainA Redox-based Superoxide Generation System using Quinone/Quinone Reductase

ChemBioChem 2018,  19, 1657-1663. 


18. N. Saha+, A. Mondal+, K. Witte, S. K. Singh, M. Müller, S. M. Husain*  Monomeric Dihydroanthaquinones: A Chemoenzymatic Approach and its (Bio)synthetic Implications for Bisnathraquinones Chem. Eur. J. 201824, 1283-1286. +equal contribution


16. L. Fürtges, D. Conradt, M. A. Schaetzle, S. K. Singh, N. Kraševec, T. L. Rižner, M. Müller,* S. M. HusainPhylogenetic Studies, Gene Cluster Analysis, and Enzymatic Reaction Support Anthrahydroquinone Reduction as the Physiological Function of Fungal 17beta-Hydroxysteroid Dehydrogenase  ChemBioChem 201618, 77-80. [Link]


15. J. Haas, M. A. Schätzle, S. M. Husain, J. Schulz-Fincke, M. Jung, W. Hummel, M. Müller, S. Lüdeke A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysates Chem. Comm. 201652, 5198-5201.


14. M. A. Schätzle, S.M. Husain, M. Müller Tetrahydroxynaphthalene Reductase – Catalytic Properties of an Enzyme Involved in Reductive Asymmetric Naphthol Dearomatization Book Chapter in Practical Methods for Biocatalysis and Biotransformations-3- 2016 Edited by Whitall, Sutton, and Kroutil

book chapter.jfif

13. D. Conradt, M. A. Schätzle, S.M. Husain, M. Müller Diversity in Reduction with Short-Chain Dehydrogenases: Tetrahydroxynaphthalene Reductase, Trihydroxynaphthalene Reductase, and Glucose Dehydrogenase Chem.Cat. Chem. 2015, 7, 3116-3120. 


12. S.M. Husain, M. A. Schätzle, S. Lüdeke, M. Müller Unprecedented Role of Hydronaphthoquinone Tautomers in Biosynthesis  Angew. Chem. Int. Ed. 201453, 9806-9811.

angew chem.gif

Mentored Publications

11. M. A. Schätzle, S. M. Husain, S. Ferlaino, M. Müller Tautomers of Anthrahydroquinones: Enzymatic Reduction and Implications for Chrysophanol, Monodictyphenone, and Related Xanthone Biosyntheses J. Am. Chem. Soc. 2012134, 14742-14745. [PDF] [Supporting info]


10. S. M. Husain, M. A. Schätzle, C. Röhr, S. Lüdeke, M. Müller Biomimetic Asymmetric Synthesis of (R)-GTRI-02 and (3S,4R)-3,4-Dihydroxy-3,4-dihydronaphthalene-1(2H)-ones  Org. Lett. 201214, 3600-3603. [PDF] [Supporting info]

9. J. Kulig, R. C. Simon, C. A. Rose, S. M. Husain, M. Häckh, S. Lüdeke, K. Zeitler, W. Kroutil, M. Pohl, D. Rother Stereoselective synthesis of bulky 1,2-diols with alcohol dehydrogenases Catal. Sci. Technol. 20122, 1580-1589.[PDF] [Supporting info]

8. M. A. Schätzle, S. Flemming, S.M. Husain, M. Richter, S. Günther, M. Müller Tetrahydroxynaphthalene Reductase – Catalytic Properties of an Enzyme involved in Reductive Asymmetric Naphthol Dearomatization Angew. Chem. Int. Ed. 201251, 2643-2646. [PDF] [Supporting info]

7. S. M. Husain,T. Stillger, P. Dünkelmann, M. Lödige, L. Walter, E. Breitling, M. Pohl, M. Bürchner,I. Krossing, M. Müller, D. Romano,F. Molinari Stereoselective reduction of 2-hydroxy ketones towards syn– and anti-1,2-Diols Adv. Synth. Catal. 2011353, 2359-2362. [PDF] [Supporting info]

From Ph.D.

6. S. Sarkar, S. M. Husain, D. Schepmann, R. Fröhlich, B. Wünsch Microwave assisted synthesis of 3-benzazepin-2-ones as building blocks for 2,3-disubstituted tetrahydro-3-benzazepines  Tetrahedron 201268, 2687-2695.[PDF]

5. S. M. Husain, R. Fröhlich, D. Schepmann, B. Wünsch Enantioselective Synthesis of a 2,2-Disubstituted Tetrahydro-3-benzazepine as Novel Receptor Antagonist Z. Naturforsch. 201065b, 191-196.

4. Asymmetric Synthesis and σ receptor affinity of enantiomerically pure 1,4-disubstituted-tetrahydro-1H-3-benzazepines 
S. M. Husain, M. T. Heim, D. Schepmann, B, Wünsch,  Tetrahedron: Asymmetry200920, 1383-1392.

3. S.M. Husain, R. Fröhlich, D. Schepmann, B. Wünsch Asymmetric Synthesis of Enantiomerically pure 2-Substituted-3-benzazepines and Their Affinity to σ1 Receptors J. Org. Chem. 200974, 2788-2793.
[PDF] [Supporting Info]

2. S. M. Husain, R. Fröhlich, B. Wünsch A very short asymmetric synthesis of enantiomerically pure methyl substituted tetrahydro-3-benzazepines Tetrahedron: Asymmetry200819, 1613-1616.

1. S. M. Husain, B. Wünsch, Synthesis of Phenylacetic Acids with 2-Oxoalkyl Substituents in ortho-Position from o-Phenylenediacetic Acid Synthesis200817, 2729-2732.

bottom of page